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Targeting miRNA-based medicines to cystic fibrosis airway epithelial cells using nanotechnology

Cystic fibrosis (CF) is an inherited disorder characterized by chronic airway inflammation. microRNAs (miRNAs) are endogenous small RNAs which act on messenger (m) RNA at a post transcriptional level, and there is a growing understanding that altered expression of miRNA is involved in the CF phenoty...

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Detalles Bibliográficos
Autores principales: McKiernan, Paul J, Cunningham, Orla, Greene, Catherine M, Cryan, Sally-Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798151/
https://www.ncbi.nlm.nih.gov/pubmed/24143095
http://dx.doi.org/10.2147/IJN.S47551