The nucleus of endothelial cell as a sensor of blood flow direction

Hemodynamic shear stresses cause endothelial cells (ECs) to polarize in the plane of the flow. Paradoxically, under strong shear flows, ECs disassemble their primary cilia, common sensors of shear, and thus must use an alternative mechanism of sensing the strength and direction of flow. In our exper...

Descripción completa

Detalles Bibliográficos
Autores principales: Tkachenko, Eugene, Gutierrez, Edgar, Saikin, Semion K., Fogelstrand, Per, Kim, Chungho, Groisman, Alex, Ginsberg, Mark H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798183/
https://www.ncbi.nlm.nih.gov/pubmed/24167710
http://dx.doi.org/10.1242/bio.20134622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798183/
https://www.ncbi.nlm.nih.gov/pubmed/24167710
http://dx.doi.org/10.1242/bio.20134622

Ejemplares similares