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Notch3 marks clonogenic mammary luminal progenitor cells in vivo

The identity of mammary stem and progenitor cells remains poorly understood, mainly as a result of the lack of robust markers. The Notch signaling pathway has been implicated in mammary gland development as well as in tumorigenesis in this tissue. Elevated expression of the Notch3 receptor has been...

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Detalles Bibliográficos
Autores principales: Lafkas, Daniel, Rodilla, Veronica, Huyghe, Mathilde, Mourao, Larissa, Kiaris, Hippokratis, Fre, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798243/
https://www.ncbi.nlm.nih.gov/pubmed/24100291
http://dx.doi.org/10.1083/jcb.201307046