Cargando…
Notch3 marks clonogenic mammary luminal progenitor cells in vivo
The identity of mammary stem and progenitor cells remains poorly understood, mainly as a result of the lack of robust markers. The Notch signaling pathway has been implicated in mammary gland development as well as in tumorigenesis in this tissue. Elevated expression of the Notch3 receptor has been...
Autores principales: | Lafkas, Daniel, Rodilla, Veronica, Huyghe, Mathilde, Mourao, Larissa, Kiaris, Hippokratis, Fre, Silvia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798243/ https://www.ncbi.nlm.nih.gov/pubmed/24100291 http://dx.doi.org/10.1083/jcb.201307046 |
Ejemplares similares
-
Luminal Progenitors Restrict Their Lineage Potential during Mammary Gland Development
por: Rodilla, Veronica, et al.
Publicado: (2015) -
Lineage tracing of Notch1-expressing cells in intestinal tumours reveals a distinct population of cancer stem cells
por: Mourao, Larissa, et al.
Publicado: (2019) -
Cellular Plasticity of Mammary Epithelial Cells Underlies Heterogeneity of Breast Cancer
por: Rodilla, Verónica, et al.
Publicado: (2018) -
Notch Lineages and Activity in Intestinal Stem Cells Determined by a New Set of Knock-In Mice
por: Fre, Silvia, et al.
Publicado: (2011) -
In vivo imaging of mammary epithelial cell dynamics in response to lineage-biased Wnt/β-catenin activation
por: Lloyd-Lewis, Bethan, et al.
Publicado: (2022)