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Pin1 promotes histone H1 dephosphorylation and stabilizes its binding to chromatin

Histone H1 plays a crucial role in stabilizing higher order chromatin structure. Transcriptional activation, DNA replication, and chromosome condensation all require changes in chromatin structure and are correlated with the phosphorylation of histone H1. In this study, we describe a novel interacti...

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Detalles Bibliográficos
Autores principales: Raghuram, Nikhil, Strickfaden, Hilmar, McDonald, Darin, Williams, Kylie, Fang, He, Mizzen, Craig, Hayes, Jeffrey J., Th’ng, John, Hendzel, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798258/
https://www.ncbi.nlm.nih.gov/pubmed/24100296
http://dx.doi.org/10.1083/jcb.201305159