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The Human Nuclear Poly(A)-Binding Protein Promotes RNA Hyperadenylation and Decay
Control of nuclear RNA stability is essential for proper gene expression, but the mechanisms governing RNA degradation in mammalian nuclei are poorly defined. In this study, we uncover a mammalian RNA decay pathway that depends on the nuclear poly(A)-binding protein (PABPN1), the poly(A) polymerases...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798265/ https://www.ncbi.nlm.nih.gov/pubmed/24146636 http://dx.doi.org/10.1371/journal.pgen.1003893 |