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Human Retrovirus Codon Usage from tRNA Point of View: Therapeutic Insights

The purpose of this study was to investigate the balance between transfer ribonucleic acid (tRNA) supply and demand in retrovirus-infected cells, seeking the best targets for antiretroviral therapy based on the hypothetical tRNA Inhibition Therapy (TRIT). Codon usage and tRNA gene data were retrieve...

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Detalles Bibliográficos
Autores principales: Frias, Diego, Monteiro-Cunha, Joana P., Mota-Miranda, Aline C., Fonseca, Vagner S., de Oliveira, Tulio, Galvao-Castro, Bernardo, Alcantara, Luiz C. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798314/
https://www.ncbi.nlm.nih.gov/pubmed/24151425
http://dx.doi.org/10.4137/BBI.S12093