Breast Tumors with Elevated Expression of 1q Candidate Genes Confer Poor Clinical Outcome and Sensitivity to Ras/PI3K Inhibition

Genomic aberrations are common in cancers and the long arm of chromosome 1 is known for its frequent amplifications in breast cancer. However, the key candidate genes of 1q, and their contribution in breast cancer pathogenesis remain unexplored. We have analyzed the gene expression profiles of 1635...

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Detalles Bibliográficos
Autores principales: Muthuswami, Muthulakshmi, Ramesh, Vignesh, Banerjee, Saikat, Viveka Thangaraj, Soundara, Periasamy, Jayaprakash, Bhaskar Rao, Divya, Barnabas, Georgina D., Raghavan, Swetha, Ganesan, Kumaresan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798322/
https://www.ncbi.nlm.nih.gov/pubmed/24147022
http://dx.doi.org/10.1371/journal.pone.0077553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798322/
https://www.ncbi.nlm.nih.gov/pubmed/24147022
http://dx.doi.org/10.1371/journal.pone.0077553

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