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Attenuation of Doxorubicin-Induced Cardiotoxicity by mdivi-1: A Mitochondrial Division/Mitophagy Inhibitor

Doxorubicin is one of the most effective anti-cancer agents. However, its use is associated with adverse cardiac effects, including cardiomyopathy and progressive heart failure. Given the multiple beneficial effects of the mitochondrial division inhibitor (mdivi-1) in a variety of pathological condi...

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Detalles Bibliográficos
Autores principales: Gharanei, Mayel, Hussain, Afthab, Janneh, Omar, Maddock, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798380/
https://www.ncbi.nlm.nih.gov/pubmed/24147064
http://dx.doi.org/10.1371/journal.pone.0077713