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Toxoplasma gondii Relies on Both Host and Parasite Isoprenoids and Can Be Rendered Sensitive to Atorvastatin

Intracellular pathogens have complex metabolic interactions with their host cells to ensure a steady supply of energy and anabolic building blocks for rapid growth. Here we use the obligate intracellular parasite Toxoplasma gondii to probe this interaction for isoprenoids, abundant lipidic compounds...

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Detalles Bibliográficos
Autores principales: Li, Zhu-Hong, Ramakrishnan, Srinivasan, Striepen, Boris, Moreno, Silvia N. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798403/
https://www.ncbi.nlm.nih.gov/pubmed/24146616
http://dx.doi.org/10.1371/journal.ppat.1003665