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miR-29b, miR-205 and miR-221 Enhance Chemosensitivity to Gemcitabine in HuH28 Human Cholangiocarcinoma Cells

BACKGROUND AND AIMS: Cholangiocarcinoma (CCA) is highly resistant to chemotherapy, including gemcitabine (Gem) treatment. MicroRNAs (miRNAs) are endogenous, non-coding, short RNAs that can regulate multiple genes expression. Some miRNAs play important roles in the chemosensitivity of tumors. Here, w...

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Detalles Bibliográficos
Autores principales: Okamoto, Kinya, Miyoshi, Kenichi, Murawaki, Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798426/
https://www.ncbi.nlm.nih.gov/pubmed/24147037
http://dx.doi.org/10.1371/journal.pone.0077623