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An Exposure to the Oxidized DNA Enhances Both Instability of Genome and Survival in Cancer Cells

BACKGROUND: Cell free DNA (cfDNA) circulates throughout the bloodstream of both healthy people and patients with various diseases and acts upon the cells. Response to cfDNA depends on concentrations and levels of the damage within cfDNA. Oxidized extracellular DNA acts as a stress signal and elicits...

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Detalles Bibliográficos
Autores principales: Kostyuk, Svetlana V., Konkova, Marina S., Ershova, Elizaveta S., Alekseeva, Anna J., Smirnova, Tatiana D., Stukalov, Sergey V., Kozhina, Ekaterina A., Shilova, Nadezda V., Zolotukhina, Tatiana V., Markova, Zhanna G., Izhevskaya, Vera L., Baranova, Ancha, Veiko, Natalia N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798467/
https://www.ncbi.nlm.nih.gov/pubmed/24147001
http://dx.doi.org/10.1371/journal.pone.0077469