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The DAF-16/FOXO Transcription Factor Functions as a Regulator of Epidermal Innate Immunity

The Caenorhabditis elegans DAF-16 transcription factor is critical for diverse biological processes, particularly longevity and stress resistance. Disruption of the DAF-2 signaling cascade promotes DAF-16 activation, and confers resistance to killing by pathogenic bacteria, such as Pseudomonas aerug...

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Detalles Bibliográficos
Autores principales: Zou, Cheng-Gang, Tu, Qiu, Niu, Jie, Ji, Xing-Lai, Zhang, Ke-Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798571/
https://www.ncbi.nlm.nih.gov/pubmed/24146615
http://dx.doi.org/10.1371/journal.ppat.1003660