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Effects of Maternal 5,10-Methylenetetrahydrofolate Reductase C677T and A1298C Polymorphisms and Tobacco Smoking on Infant Birth Weight in a Japanese Population

BACKGROUND: Intracellular folate hemostasis depends on the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene. Because 5,10-MTHFR 677TT homozygosity and tobacco smoking are associated with low folate status, we tested the hypothesis that smoking in mothers with 5,10-MTHFR C677T or A1298C polymorp...

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Detalles Bibliográficos
Autores principales: Yila, Thamar Ayo, Sasaki, Seiko, Miyashita, Chihiro, Braimoh, Titilola Serifat, Kashino, Ikuko, Kobayashi, Sumitaka, Okada, Emiko, Baba, Toshiaki, Yoshioka, Eiji, Minakami, Hisanori, Endo, Toshiaki, Sengoku, Kazuo, Kishi, Reiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Epidemiological Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798587/
https://www.ncbi.nlm.nih.gov/pubmed/22277790
http://dx.doi.org/10.2188/jea.JE20110039