Antifibrotic effects of crocetin in scleroderma fibroblasts and in bleomycin-induced sclerotic mice

OBJECTIVE: To investigate the antifibrotic effects of crocetin in scleroderma fibroblasts and in sclerotic mice. METHODS: Skin fibroblasts that were isolated from three systemic scleroderma (SSc) patients and three healthy subjects were treated with crocetin (0.1, 1 or 10 μM). Cell proliferation was...

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Detalles Bibliográficos
Autores principales: Song, Yinghua, Zhu, Lubing, Li, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2013
Materias:
Basic Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798612/
https://www.ncbi.nlm.nih.gov/pubmed/24212843
http://dx.doi.org/10.6061/clinics/2013(10)10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798612/
https://www.ncbi.nlm.nih.gov/pubmed/24212843
http://dx.doi.org/10.6061/clinics/2013(10)10

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