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Immunosenescence is associated with altered gene expression and epigenetic regulation in primary and secondary immune organs
Deterioration of the immune system (immunosenescence) with age is associated with an increased susceptibility to infection, autoimmune disease and cancer, and reduced responsiveness to vaccination. Immunosenescence entails a reduced supply of naïve T cells from the thymus and increased specializatio...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798808/ https://www.ncbi.nlm.nih.gov/pubmed/24151501 http://dx.doi.org/10.3389/fgene.2013.00211 |