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Toward a Molecular Classification of Colorectal Cancer: The Role of MGMT
O(6)-methylguanine DNA methyltransferase (MGMT) is a DNA repair enzyme with the ability to protect cells from DNA mutations by removing alkyl groups from the O(6) position of guanine. Colon mucosa is exposed to the direct effects of environmental carcinogens and therefore maintaining a proficient DN...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798865/ https://www.ncbi.nlm.nih.gov/pubmed/24151575 http://dx.doi.org/10.3389/fonc.2013.00266 |