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Vessel co-option in primary human tumors and metastases: an obstacle to effective anti-angiogenic treatment?

Angiogenesis has been regarded as essential for tumor growth and progression. Studies of many human tumors, however, suggest that their microcirculation may be provided by nonsprouting vessels and that a variety of tumors can grow and metastasize without angiogenesis. Vessel co-option, where tumor c...

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Detalles Bibliográficos
Autores principales: Donnem, Tom, Hu, Jiangting, Ferguson, Mary, Adighibe, Omanma, Snell, Cameron, Harris, Adrian L, Gatter, Kevin C, Pezzella, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Science Inc 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799277/
https://www.ncbi.nlm.nih.gov/pubmed/24156015
http://dx.doi.org/10.1002/cam4.105