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Inhibition of MMP14 potentiates the therapeutic effect of temozolomide and radiation in gliomas

Metalloproteinases are membrane-bound proteins that play a role in the cellular responses to antiglioma therapy. Previously, it has been shown that treatment of glioma cells with temozolomide (TMZ) and radiation (XRT) induces the expression of metalloproteinase 14 (MMP14). To investigate the role of...

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Detalles Bibliográficos
Autores principales: Ulasov, Ilya, Thaci, Bart, Sarvaiya, Purvaba, Yi, Ruiyang, Guo, Donna, Auffinger, Brenda, Pytel, Peter, Zhang, Lingjiao, Kim, Chung Kwon, Borovjagin, Anton, Dey, Mahua, Han, Yu, Baryshnikov, Anatoly Y, Lesniak, Maciej S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Science Inc 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799280/
https://www.ncbi.nlm.nih.gov/pubmed/24156018
http://dx.doi.org/10.1002/cam4.104