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Inhibition of MMP14 potentiates the therapeutic effect of temozolomide and radiation in gliomas
Metalloproteinases are membrane-bound proteins that play a role in the cellular responses to antiglioma therapy. Previously, it has been shown that treatment of glioma cells with temozolomide (TMZ) and radiation (XRT) induces the expression of metalloproteinase 14 (MMP14). To investigate the role of...
Autores principales: | Ulasov, Ilya, Thaci, Bart, Sarvaiya, Purvaba, Yi, Ruiyang, Guo, Donna, Auffinger, Brenda, Pytel, Peter, Zhang, Lingjiao, Kim, Chung Kwon, Borovjagin, Anton, Dey, Mahua, Han, Yu, Baryshnikov, Anatoly Y, Lesniak, Maciej S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Science Inc
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799280/ https://www.ncbi.nlm.nih.gov/pubmed/24156018 http://dx.doi.org/10.1002/cam4.104 |
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