Temporal regulation of the Mus81-Mms4 endonuclease ensures cell survival under conditions of DNA damage

The structure-specific Mus81-Eme1/Mms4 endonuclease contributes importantly to DNA repair and genome integrity maintenance. Here, using budding yeast, we have studied its function and regulation during the cellular response to DNA damage and show that this endonuclease is necessary for successful ch...

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Detalles Bibliográficos
Autores principales: Saugar, Irene, Vázquez, María Victoria, Gallo-Fernández, María, Ortiz-Bazán, María Ángeles, Segurado, Mónica, Calzada, Arturo, Tercero, José Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799426/
https://www.ncbi.nlm.nih.gov/pubmed/23901010
http://dx.doi.org/10.1093/nar/gkt645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799426/
https://www.ncbi.nlm.nih.gov/pubmed/23901010
http://dx.doi.org/10.1093/nar/gkt645

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