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High-resolution definition of the Vibrio cholerae essential gene set with hidden Markov model–based analyses of transposon-insertion sequencing data

The coupling of high-density transposon mutagenesis to high-throughput DNA sequencing (transposon-insertion sequencing) enables simultaneous and genome-wide assessment of the contributions of individual loci to bacterial growth and survival. We have refined analysis of transposon-insertion sequencin...

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Detalles Bibliográficos
Autores principales: Chao, Michael C., Pritchard, Justin R., Zhang, Yanjia J., Rubin, Eric J., Livny, Jonathan, Davis, Brigid M., Waldor, Matthew K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799429/
https://www.ncbi.nlm.nih.gov/pubmed/23901011
http://dx.doi.org/10.1093/nar/gkt654