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XPD-dependent activation of apoptosis in response to triplex-induced DNA damage
DNA sequences capable of forming triplexes are prevalent in the human genome and have been found to be intrinsically mutagenic. Consequently, a balance between DNA repair and apoptosis is critical to counteract their effect on genomic integrity. Using triplex-forming oligonucleotides to syntheticall...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799437/ https://www.ncbi.nlm.nih.gov/pubmed/23913414 http://dx.doi.org/10.1093/nar/gkt670 |