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Transcription activator like effector (TALE)-directed piggyBac transposition in human cells
Insertional therapies have shown great potential for combating genetic disease and safer methods would undoubtedly broaden the variety of possible illness that can be treated. A major challenge that remains is reducing the risk of insertional mutagenesis due to random insertion by both viral and non...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799441/ https://www.ncbi.nlm.nih.gov/pubmed/23921635 http://dx.doi.org/10.1093/nar/gkt677 |