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Transcription activator like effector (TALE)-directed piggyBac transposition in human cells

Insertional therapies have shown great potential for combating genetic disease and safer methods would undoubtedly broaden the variety of possible illness that can be treated. A major challenge that remains is reducing the risk of insertional mutagenesis due to random insertion by both viral and non...

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Detalles Bibliográficos
Autores principales: Owens, Jesse B., Mauro, Damiano, Stoytchev, Ilko, Bhakta, Mital S., Kim, Moon-Soo, Segal, David J., Moisyadi, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799441/
https://www.ncbi.nlm.nih.gov/pubmed/23921635
http://dx.doi.org/10.1093/nar/gkt677