Systems biology of Ewing sarcoma: a network model of EWS-FLI1 effect on proliferation and apoptosis

Ewing sarcoma is the second most frequent pediatric bone tumor. In most of the patients, a chromosomal translocation leads to the expression of the EWS-FLI1 chimeric transcription factor that is the major oncogene in this pathology. Relative genetic simplicity of Ewing sarcoma makes it particularly...

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Detalles Bibliográficos
Autores principales: Stoll, Gautier, Surdez, Didier, Tirode, Franck, Laud, Karine, Barillot, Emmanuel, Zinovyev, Andrei, Delattre, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799442/
https://www.ncbi.nlm.nih.gov/pubmed/23935076
http://dx.doi.org/10.1093/nar/gkt678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799442/
https://www.ncbi.nlm.nih.gov/pubmed/23935076
http://dx.doi.org/10.1093/nar/gkt678

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