Receptor-mediated delivery of engineered nucleases for genome modification

Engineered nucleases, which incise the genome at predetermined sites, have a number of laboratory and clinical applications. There is, however, a need for better methods for controlled intracellular delivery of nucleases. Here, we demonstrate a method for ligand-mediated delivery of zinc finger nucl...

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Detalles Bibliográficos
Autores principales: Chen, Zhong, Jaafar, Lahcen, Agyekum, Davies G., Xiao, Haiyan, Wade, Marlene F., Kumaran, R. Ileng, Spector, David L., Bao, Gang, Porteus, Matthew H., Dynan, William S., Meiler, Steffen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799454/
https://www.ncbi.nlm.nih.gov/pubmed/23956220
http://dx.doi.org/10.1093/nar/gkt710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799454/
https://www.ncbi.nlm.nih.gov/pubmed/23956220
http://dx.doi.org/10.1093/nar/gkt710

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