Heterogeneous staining: a tool for studies of how fluorescent dyes affect the physical properties of DNA

The commonly used fluorescent dye YOYO-1 (YOYO) has, using bulk techniques, been demonstrated to stain DNA heterogeneously at substoichiometric concentrations. We here, using nanofluidic channels and fluorescence microscopy, investigate the heterogeneous staining on the single DNA molecule level and...

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Detalles Bibliográficos
Autores principales: Nyberg, Lena, Persson, Fredrik, Åkerman, Björn, Westerlund, Fredrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799460/
https://www.ncbi.nlm.nih.gov/pubmed/23975199
http://dx.doi.org/10.1093/nar/gkt755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799460/
https://www.ncbi.nlm.nih.gov/pubmed/23975199
http://dx.doi.org/10.1093/nar/gkt755

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