STIM1 and STIM2-mediated Ca(2+) influx regulates antitumour immunity by CD8(+) T cells

Store-operated calcium entry (SOCE) through Ca(2+) release-activated Ca(2+) (CRAC) channels regulates the function of many immune cells. Patients with loss-of-function mutations in the CRAC channel genes ORAI1 or STIM1 are immunodeficient and are prone to develop virus-associated tumours. This and t...

Descripción completa

Detalles Bibliográficos
Autores principales: Weidinger, Carl, Shaw, Patrick J, Feske, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799488/
https://www.ncbi.nlm.nih.gov/pubmed/23922331
http://dx.doi.org/10.1002/emmm.201302989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799488/
https://www.ncbi.nlm.nih.gov/pubmed/23922331
http://dx.doi.org/10.1002/emmm.201302989

Ejemplares similares