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STIM1 and STIM2-mediated Ca(2+) influx regulates antitumour immunity by CD8(+) T cells

Store-operated calcium entry (SOCE) through Ca(2+) release-activated Ca(2+) (CRAC) channels regulates the function of many immune cells. Patients with loss-of-function mutations in the CRAC channel genes ORAI1 or STIM1 are immunodeficient and are prone to develop virus-associated tumours. This and t...

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Detalles Bibliográficos
Autores principales:	Weidinger, Carl, Shaw, Patrick J, Feske, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2013
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799488/ https://www.ncbi.nlm.nih.gov/pubmed/23922331 http://dx.doi.org/10.1002/emmm.201302989

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