Integrative analysis revealed the molecular mechanism underlying RBM10-mediated splicing regulation

RBM10 encodes an RNA binding protein. Mutations in RBM10 are known to cause multiple congenital anomaly syndrome in male humans, the TARP syndrome. However, the molecular function of RBM10 is unknown. Here we used PAR-CLIP to identify thousands of binding sites of RBM10 and observed significant RBM1...

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Detalles Bibliográficos
Autores principales: Wang, Yongbo, Gogol-Döring, Andreas, Hu, Hao, Fröhler, Sebastian, Ma, Yunxia, Jens, Marvin, Maaskola, Jonas, Murakawa, Yasuhiro, Quedenau, Claudia, Landthaler, Markus, Kalscheuer, Vera, Wieczorek, Dagmar, Wang, Yang, Hu, Yuhui, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799496/
https://www.ncbi.nlm.nih.gov/pubmed/24000153
http://dx.doi.org/10.1002/emmm.201302663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799496/
https://www.ncbi.nlm.nih.gov/pubmed/24000153
http://dx.doi.org/10.1002/emmm.201302663

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