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Integrative analysis revealed the molecular mechanism underlying RBM10-mediated splicing regulation
RBM10 encodes an RNA binding protein. Mutations in RBM10 are known to cause multiple congenital anomaly syndrome in male humans, the TARP syndrome. However, the molecular function of RBM10 is unknown. Here we used PAR-CLIP to identify thousands of binding sites of RBM10 and observed significant RBM1...
Autores principales: | Wang, Yongbo, Gogol-Döring, Andreas, Hu, Hao, Fröhler, Sebastian, Ma, Yunxia, Jens, Marvin, Maaskola, Jonas, Murakawa, Yasuhiro, Quedenau, Claudia, Landthaler, Markus, Kalscheuer, Vera, Wieczorek, Dagmar, Wang, Yang, Hu, Yuhui, Chen, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799496/ https://www.ncbi.nlm.nih.gov/pubmed/24000153 http://dx.doi.org/10.1002/emmm.201302663 |
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