Prevalence of Mycobacterium avium in Slaughter Pigs Based on Serological Monitoring Results and Bacteriological Validation

Mycobacterium avium (MA) is a potential food safety hazard in pigs. Blood samples of slaughtered pigs in the Netherlands and Germany were tested for the presence of MA antibodies to estimate the serological prevalence in the tested population. In the Dutch and German population 1.0% and 1.7% samples...

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Autores principales: Hiller, Anne, Oorburg, Derk, Wisselink, Henk J., van Solt-Smits, Conny B., Urlings, Bert, Klein, Günter, Althoff, Gereon Schulze, Heres, Lourens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799521/
https://www.ncbi.nlm.nih.gov/pubmed/23999550
http://dx.doi.org/10.3390/ijerph10094027
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author Hiller, Anne
Oorburg, Derk
Wisselink, Henk J.
van Solt-Smits, Conny B.
Urlings, Bert
Klein, Günter
Althoff, Gereon Schulze
Heres, Lourens
author_facet Hiller, Anne
Oorburg, Derk
Wisselink, Henk J.
van Solt-Smits, Conny B.
Urlings, Bert
Klein, Günter
Althoff, Gereon Schulze
Heres, Lourens
author_sort Hiller, Anne
collection PubMed
description Mycobacterium avium (MA) is a potential food safety hazard in pigs. Blood samples of slaughtered pigs in the Netherlands and Germany were tested for the presence of MA antibodies to estimate the serological prevalence in the tested population. In the Dutch and German population 1.0% and 1.7% samples were positive, and 0.5% and 17.4% of the herds were at risk for having a MA infection respectively. The validity of the applied MA-ELISA was evaluated under field conditions. The specificity of the MA-ELISA was high (>98.4%). The average herd sensitivity was 18%. In the affected herds on average 50% of the animals were tested bacteriological positive for MA. It can be concluded that serological screening for the presence of MA antibodies is capable of identifying pig populations that are at risk for a MA infection.
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spelling pubmed-37995212013-10-21 Prevalence of Mycobacterium avium in Slaughter Pigs Based on Serological Monitoring Results and Bacteriological Validation Hiller, Anne Oorburg, Derk Wisselink, Henk J. van Solt-Smits, Conny B. Urlings, Bert Klein, Günter Althoff, Gereon Schulze Heres, Lourens Int J Environ Res Public Health Article Mycobacterium avium (MA) is a potential food safety hazard in pigs. Blood samples of slaughtered pigs in the Netherlands and Germany were tested for the presence of MA antibodies to estimate the serological prevalence in the tested population. In the Dutch and German population 1.0% and 1.7% samples were positive, and 0.5% and 17.4% of the herds were at risk for having a MA infection respectively. The validity of the applied MA-ELISA was evaluated under field conditions. The specificity of the MA-ELISA was high (>98.4%). The average herd sensitivity was 18%. In the affected herds on average 50% of the animals were tested bacteriological positive for MA. It can be concluded that serological screening for the presence of MA antibodies is capable of identifying pig populations that are at risk for a MA infection. MDPI 2013-08-30 2013-09 /pmc/articles/PMC3799521/ /pubmed/23999550 http://dx.doi.org/10.3390/ijerph10094027 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Hiller, Anne
Oorburg, Derk
Wisselink, Henk J.
van Solt-Smits, Conny B.
Urlings, Bert
Klein, Günter
Althoff, Gereon Schulze
Heres, Lourens
Prevalence of Mycobacterium avium in Slaughter Pigs Based on Serological Monitoring Results and Bacteriological Validation
title Prevalence of Mycobacterium avium in Slaughter Pigs Based on Serological Monitoring Results and Bacteriological Validation
title_full Prevalence of Mycobacterium avium in Slaughter Pigs Based on Serological Monitoring Results and Bacteriological Validation
title_fullStr Prevalence of Mycobacterium avium in Slaughter Pigs Based on Serological Monitoring Results and Bacteriological Validation
title_full_unstemmed Prevalence of Mycobacterium avium in Slaughter Pigs Based on Serological Monitoring Results and Bacteriological Validation
title_short Prevalence of Mycobacterium avium in Slaughter Pigs Based on Serological Monitoring Results and Bacteriological Validation
title_sort prevalence of mycobacterium avium in slaughter pigs based on serological monitoring results and bacteriological validation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799521/
https://www.ncbi.nlm.nih.gov/pubmed/23999550
http://dx.doi.org/10.3390/ijerph10094027
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