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Exploring the membrane topology of prohormone convertase 1 in AtT20 Cells: in situ analysis by immunofluorescence microscopy

Prohormone convertase 1 (PC1) was previously characterized as a partially transmembrane protein in purified chromaffin granules of bovine adrenal medulla1. This was challenged with experiments on transfected PC1 in COS1 cells, a non-endocrine cell line2. To address this issue, we undertook to analyz...

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Detalles Bibliográficos
Autores principales: Cawley, Niamh X, Sridhar, Meera, Hong, Hong, Loh, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799554/
https://www.ncbi.nlm.nih.gov/pubmed/24163733
http://dx.doi.org/10.12688/f1000research.1-9.v1