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VBP15, a novel anti-inflammatory and membrane-stabilizer, improves muscular dystrophy without side effects

Absence of dystrophin makes skeletal muscle more susceptible to injury, resulting in breaches of the plasma membrane and chronic inflammation in Duchenne muscular dystrophy (DMD). Current management by glucocorticoids has unclear molecular benefits and harsh side effects. It is uncertain whether the...

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Detalles Bibliográficos
Autores principales: Heier, Christopher R, Damsker, Jesse M, Yu, Qing, Dillingham, Blythe C, Huynh, Tony, Van der Meulen, Jack H, Sali, Arpana, Miller, Brittany K, Phadke, Aditi, Scheffer, Luana, Quinn, James, Tatem, Kathleen, Jordan, Sarah, Dadgar, Sherry, Rodriguez, Olga C, Albanese, Chris, Calhoun, Michael, Gordish-Dressman, Heather, Jaiswal, Jyoti K, Connor, Edward M, McCall, John M, Hoffman, Eric P, Reeves, Erica K M, Nagaraju, Kanneboyina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799580/
https://www.ncbi.nlm.nih.gov/pubmed/24014378
http://dx.doi.org/10.1002/emmm.201302621