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VBP15, a novel anti-inflammatory and membrane-stabilizer, improves muscular dystrophy without side effects
Absence of dystrophin makes skeletal muscle more susceptible to injury, resulting in breaches of the plasma membrane and chronic inflammation in Duchenne muscular dystrophy (DMD). Current management by glucocorticoids has unclear molecular benefits and harsh side effects. It is uncertain whether the...
Autores principales: | Heier, Christopher R, Damsker, Jesse M, Yu, Qing, Dillingham, Blythe C, Huynh, Tony, Van der Meulen, Jack H, Sali, Arpana, Miller, Brittany K, Phadke, Aditi, Scheffer, Luana, Quinn, James, Tatem, Kathleen, Jordan, Sarah, Dadgar, Sherry, Rodriguez, Olga C, Albanese, Chris, Calhoun, Michael, Gordish-Dressman, Heather, Jaiswal, Jyoti K, Connor, Edward M, McCall, John M, Hoffman, Eric P, Reeves, Erica K M, Nagaraju, Kanneboyina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799580/ https://www.ncbi.nlm.nih.gov/pubmed/24014378 http://dx.doi.org/10.1002/emmm.201302621 |
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