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MicroRNA-146b promotes adipogenesis by suppressing the SIRT1-FOXO1 cascade

Sirtuin 1 (SIRT1) plays a critical role in the maintenance of metabolic homeostasis and promotes fat mobilization in white adipose tissue. However, regulation of SIRT1 during adipogenesis, particularly through microRNAs, remains unclear. We observed that miR-146b expression was markedly increased du...

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Detalles Bibliográficos
Autores principales: Ahn, Jiyun, Lee, Hyunjung, Jung, Chang Hwa, Jeon, Tae Il, Ha, Tae Youl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799582/
https://www.ncbi.nlm.nih.gov/pubmed/24009212
http://dx.doi.org/10.1002/emmm.201302647