Protein Tyrosine Phosphatase 1B and Insulin Resistance: Role of Endoplasmic Reticulum Stress/Reactive Oxygen Species/Nuclear Factor Kappa B Axis

Obesity-induced endoplasmic reticulum (ER) stress has been proposed as an important pathway in the development of insulin resistance. Protein-tyrosine phosphatase 1B (PTP1B) is a negative regulator of insulin signaling and is tethered to the ER-membrane. The aim of the study was to determine the mec...

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Detalles Bibliográficos
Autores principales: Panzhinskiy, Evgeniy, Ren, Jun, Nair, Sreejayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799617/
https://www.ncbi.nlm.nih.gov/pubmed/24204775
http://dx.doi.org/10.1371/journal.pone.0077228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799617/
https://www.ncbi.nlm.nih.gov/pubmed/24204775
http://dx.doi.org/10.1371/journal.pone.0077228

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