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Ligation of Signal Inhibitory Receptor on Leukocytes-1 Suppresses the Release of Neutrophil Extracellular Traps in Systemic Lupus Erythematosus

Neutrophil extracellular traps (NETs) have been implicated in the pathogenesis of systemic Lupus erythematosus (SLE), since netting neutrophils release potentially immunogenic autoantigens including histones, LL37, human neutrophil peptide (HNP), and self-DNA. In turn, these NETs activate plasmacyto...

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Detalles Bibliográficos
Autores principales: Van Avondt, Kristof, Fritsch-Stork, Ruth, Derksen, Ronald H. W. M., Meyaard, Linde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799702/
https://www.ncbi.nlm.nih.gov/pubmed/24205237
http://dx.doi.org/10.1371/journal.pone.0078459