Inhibition of cdk9 during Herpes Simplex Virus 1 Infection Impedes Viral Transcription

During herpes simplex virus 1 (HSV-1) infection there is a loss of the serine-2 phosphorylated form of RNA polymerase II (RNAP II) found in elongation complexes. This occurs in part because RNAP II undergoes ubiquitination and proteasomal degradation during times of highly active viral transcription...

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Detalles Bibliográficos
Autores principales: Ou, Mark, Sandri-Goldin, Rozanne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799718/
https://www.ncbi.nlm.nih.gov/pubmed/24205359
http://dx.doi.org/10.1371/journal.pone.0079007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799718/
https://www.ncbi.nlm.nih.gov/pubmed/24205359
http://dx.doi.org/10.1371/journal.pone.0079007

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