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Spleen-Dependent Regulation of Antigenic Variation in Malaria Parasites: Plasmodium knowlesi SICAvar Expression Profiles in Splenic and Asplenic Hosts

BACKGROUND: Antigenic variation by malaria parasites was first described in Plasmodium knowlesi, which infects humans and macaque monkeys, and subsequently in P. falciparum, the most virulent human parasite. The schizont-infected cell agglutination (SICA) variant proteins encoded by the SICAvar mult...

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Detalles Bibliográficos
Autores principales: Lapp, Stacey A., Korir-Morrison, Cindy, Jiang, Jianlin, Bai, Yaohui, Corredor, Vladimir, Galinski, Mary R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799730/
https://www.ncbi.nlm.nih.gov/pubmed/24205067
http://dx.doi.org/10.1371/journal.pone.0078014