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Autophagic Vacuolation Induced by Excess ROS Generation in HABP1/p32/gC1qR Overexpressing Fibroblasts and Its Reversal by Polymeric Hyaluronan

The ubiquitous hyaladherin, hyaluronan-binding protein 1 (HABP1/p32/gC1qR) upon stable overexpression in normal fibroblasts (F-HABP07) has been reported to induce mitochondrial dysfunction, growth retardation and apoptosis after 72 h of growth. HABP1 has been observed to accumulate in the mitochondr...

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Detalles Bibliográficos
Autores principales: Saha, Paramita, Chowdhury, Anindya Roy, Dutta, Shubhra, Chatterjee, Soumya, Ghosh, Ilora, Datta, Kasturi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799741/
https://www.ncbi.nlm.nih.gov/pubmed/24205125
http://dx.doi.org/10.1371/journal.pone.0078131