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Polo-Like Kinase 1 (PLK1) Is Involved in Toll-like Receptor (TLR)-Mediated TNF-α Production in Monocytic THP-1 Cells

Polo-like kinases (PLKs) have been reported to be essential components of anti-viral pathways. However, the role of PLKs in the production of pro-inflammatory cytokines induced by TLR activation is uncertain. We report here that monocytic THP-1 cells expressed PLK1, PLK2, PLK3 and PLK4. When THP-1 c...

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Detalles Bibliográficos
Autores principales: Hu, Jinyue, Wang, Guihua, Liu, Xueting, Zhou, Lina, Jiang, Manli, Yang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799749/
https://www.ncbi.nlm.nih.gov/pubmed/24205328
http://dx.doi.org/10.1371/journal.pone.0078832