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Maraviroc Attenuates Trauma-Hemorrhage-Induced Hepatic Injury through PPAR Gamma-Dependent Pathway in Rats

Maraviroc is a CC-chemokine receptor 5 (CCR5) antagonist with potent antiviral and cancer preventive effects. Recent evidence suggests that the co-existence of CCR5 in various cell types is involved in inflammation. However, the effects that CCR5 antagonists produce in trauma-hemorrhage remain unkno...

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Detalles Bibliográficos
Autores principales: Liu, Fu-Chao, Tsai, Yung-Fong, Yu, Huang-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799750/
https://www.ncbi.nlm.nih.gov/pubmed/24205332
http://dx.doi.org/10.1371/journal.pone.0078861