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Potential for Interdependent Development of tRNA Determinants for Aminoacylation and Ribosome Decoding

Although the nucleotides in tRNA required for aminoacylation are conserved in evolution, bacterial aminoacyl-tRNA synthetases (aaRSs) are unable to acylate eukaryotic tRNA. The cross-species barrier may be due to the absence of eukaryote-specific domains from bacterial aaRSs. Here we show that while...

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Detalles Bibliográficos
Autores principales: Liu, Cuiping, Gamper, Howard, Liu, Hanqing, Cooperman, Barry S., Hou, Ya-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799875/
https://www.ncbi.nlm.nih.gov/pubmed/21629262
http://dx.doi.org/10.1038/ncomms1331