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Potential for Interdependent Development of tRNA Determinants for Aminoacylation and Ribosome Decoding
Although the nucleotides in tRNA required for aminoacylation are conserved in evolution, bacterial aminoacyl-tRNA synthetases (aaRSs) are unable to acylate eukaryotic tRNA. The cross-species barrier may be due to the absence of eukaryote-specific domains from bacterial aaRSs. Here we show that while...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799875/ https://www.ncbi.nlm.nih.gov/pubmed/21629262 http://dx.doi.org/10.1038/ncomms1331 |