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Differential regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros

C2H2 zinc fingers are found in several transcriptional regulators in the immune system. However, these proteins usually contain more fingers than are needed for stable DNA binding, suggesting that different fingers regulate different genes and functions. Mice lacking finger 1 or finger 4 of Ikaros e...

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Detalles Bibliográficos
Autores principales: Schjerven, Hilde, McLaughlin, Jami, Arenzana, Teresita L., Frietze, Seth, Cheng, Donghui, Wadsworth, Sarah, Lawson, Gregory W., Bensinger, Steven J., Farnham, Peggy J., Witte, Owen N., Smale, Stephen T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800053/
https://www.ncbi.nlm.nih.gov/pubmed/24013668
http://dx.doi.org/10.1038/ni.2707