Discovery of a Potent and Selective DDR1 Receptor Tyrosine Kinase Inhibitor

[Image: see text] The DDR1 receptor tyrosine kinase is activated by matrix collagens and has been implicated in numerous cellular functions such as proliferation, differentiation, adhesion, migration, and invasion. Here we report the discovery of a potent and selective DDR1 inhibitor, DDR1-IN-1, and...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Hyung-Gu, Tan, Li, Weisberg, Ellen L., Liu, Feiyang, Canning, Peter, Choi, Hwan Geun, Ezell, Scott A., Wu, Hong, Zhao, Zheng, Wang, Jinhua, Mandinova, Anna, Griffin, James D., Bullock, Alex N., Liu, Qingsong, Lee, Sam W., Gray, Nathanael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800496/
https://www.ncbi.nlm.nih.gov/pubmed/23899692
http://dx.doi.org/10.1021/cb400430t

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800496/
https://www.ncbi.nlm.nih.gov/pubmed/23899692
http://dx.doi.org/10.1021/cb400430t

Ejemplares similares