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15-deoxy-Δ(12,14)-prostaglandin J(2) Down-Regulates Activin-Induced Activin Receptor, Smad, and Cytokines Expression via Suppression of NF-κB and MAPK Signaling in HepG2 Cells

15-Deoxy-Δ(12,14)-prostaglandin J(2) (15d-PGJ(2)) and activin are implicated in the control of apoptosis, cell proliferation, and inflammation in cells. We examined both the mechanism by which 15d-PGJ(2) regulates the transcription of activin-induced activin receptors (ActR) and Smads in HepG2 cells...

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Detalles Bibliográficos
Autores principales: Park, Seung-Won, Cho, Chunghee, Cho, Byung-Nam, Kim, Youngchul, Goo, Tae Won, Kim, Young Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800567/
https://www.ncbi.nlm.nih.gov/pubmed/24204381
http://dx.doi.org/10.1155/2013/751261