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15-deoxy-Δ(12,14)-prostaglandin J(2) Down-Regulates Activin-Induced Activin Receptor, Smad, and Cytokines Expression via Suppression of NF-κB and MAPK Signaling in HepG2 Cells
15-Deoxy-Δ(12,14)-prostaglandin J(2) (15d-PGJ(2)) and activin are implicated in the control of apoptosis, cell proliferation, and inflammation in cells. We examined both the mechanism by which 15d-PGJ(2) regulates the transcription of activin-induced activin receptors (ActR) and Smads in HepG2 cells...
Autores principales: | Park, Seung-Won, Cho, Chunghee, Cho, Byung-Nam, Kim, Youngchul, Goo, Tae Won, Kim, Young Il |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800567/ https://www.ncbi.nlm.nih.gov/pubmed/24204381 http://dx.doi.org/10.1155/2013/751261 |
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