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Neuroprotective Effects of Hesperidin, a Plant Flavanone, on Rotenone-Induced Oxidative Stress and Apoptosis in a Cellular Model for Parkinson's Disease

Rotenone a widely used pesticide that inhibits mitochondrial complex I has been used to investigate the pathobiology of PD both in vitro and in vivo. Studies have shown that the neurotoxicity of rotenone may be related to its ability to generate reactive oxygen species (ROS), leading to neuronal apo...

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Detalles Bibliográficos
Autores principales: Tamilselvam, Kuppusamy, Braidy, Nady, Manivasagam, Thamilarasan, Essa, Musthafa Mohamed, Prasad, Nagarajan Rajendra, Karthikeyan, Subburayan, Thenmozhi, Arokyasamy Justin, Selvaraju, Subash, Guillemin, Gilles J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800605/
https://www.ncbi.nlm.nih.gov/pubmed/24205431
http://dx.doi.org/10.1155/2013/102741